MEG-UK Partnership

MEG-UK Partnership

All eight MEG centres in the UK have come together in a partnership with the aim of building MEG clinical research capacity in the UK. The collaboration is supported by the Medical Research Council (MRC), and is co-funded by the Engineering and Physical Sciences Research Council (EPSRC). The partnership consists of Aston, Cambridge Cognition and brain Sciences Unit, Cardiff, Glasgow, Nottingham, Oxford, University College London, and York. As well as supporting a cohort of doctoral students, providing a unified training courses, and developing standardised data acquisition and analysis pipelines, one of the key research goals is to establish a normative database using common protocols across sites.

Each of the collaborating sites will scan 80 individuals to yield a total of 640 datasets, primarily comprised of healthy volunteers. The ability to make valid comparisons with clinical populations requires characterisation of inter-individual variability in a healthy cohort using the same protocols and analysis pipelines. The standardised protocols will involve a range of validated tasks involving sensory, cognitive, and motor tasks, as well as resting-state recordings. The project will address critical aims of the partnership in terms of research integration, and will engender development of a principled approach to cross-site collaboration whereby it is possible to pool data from different scanner platforms, assess the reliability of measures and develop common analysis pipelines. The process will also establish standards for future cross-site collaborations to ensure data is collected and curated appropriately to enable data sharing and linking with other imaging modalities.

Investigators & Collaborators

The Brain & Cognition site participates in this partnership through OHBA. Kia Nobre and Mark Woolrich (OHBA) act as principal investigators. Simone Heideman is the doctoral student based at Oxford.

Other principal investigators include: Krish Singh (Cardiff, lead applicant), Paul Furlong (Aston), Ian Holliday (Aston), Klaus Kessler (Aston), Richard Henson (Cambridge), Yuri Shytrov (Cambridge), Khalid Hamandi (Cardiff), Joachim Gross (Glasgow), Peter Ulhaas (Glasgow), Peter Morris (Nottingham), Matthew Brookes (Nottingham), Gareth Barnes (UCL), Vladimir Litvak (UCL), Gary Green (York),

Doctoral Students are: Bethany Routley (Cardiff), Michael Hall (Aston), Lorenzo Magazzini (Cardiff), Rebecca Beresford (Cambridge), Kevin Prinsloo (Glasgow), Benjamin Hunt (Nottingham), Simone Heideman (Oxford), Sofie Meyer (UCL), Ioannis Papanikolaou (York).

Funding

The collaboration is supported by the Medical Research Council (MRC), and is co-funded by the Engineering and Physical Sciences Research Council (EPSRC). The partnership consists of Aston, Cambridge Cognition and brain Sciences Unit, Cardiff, Glasgow, Nottingham, Oxford, University College London, and York.

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